Persistence of acanthamoeba antigen following acanthamoeba keratitis

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Persistence of acanthamoeba antigen following acanthamoeba keratitis.

AIM To investigate the hypothesis that persistent corneal and scleral inflammation following acanthamoeba keratitis is not always caused by active amoebic infection but can be due to persisting acanthamoebic antigens METHODS 24 lamellar corneal biopsy and penetrating keratoplasty specimens were obtained from 14 consecutive patients at various stages of their disease and divided for microscopy...

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Acanthamoeba endophthalmitis following penetrating keratoplasty for Acanthamoeba keratitis.

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[Acanthamoeba keratitis].

Three patients, women aged 69, 25 and 30 years, with refractory keratitis were found to have a rare infection with Acanthamoeba. All wore soft contact lenses. The frequency of Acanthamoeba keratitis increased in recent years. At present, an efficacious antiprotozoal therapy is available, for instance in the form of polyhexamethylene biguanide and propamidine. In cases of refractory keratitis, t...

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Laboratory investigation of Acanthamoeba keratitis.

Following the diagnosis of Acanthamoeba keratitis in a contact lens wearer, the antimicrobial susceptibility of the clinical isolate and the environmental source of the infection were investigated. Contrary to previous reports, in vitro antimicrobial testing showed that the infecting strain was inherently resistant to propamidine isethionate. Restriction endonuclease digestion analysis of Acant...

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Acanthamoeba keratitis successfully treated medically.

The first medical cure of a corneal infection due to an Acanthamoeba species is reported. The 44-year-old patient developed a suppurative keratitis associated with an epithelial defect, hypopyon, and secondary glaucoma. Acanthamoeba was confirmed as the causative agent four months after presentation when positive cultures were obtained from the cornea and from the conjunctiva. Sensitivity studi...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2001

ISSN: 0007-1161

DOI: 10.1136/bjo.85.3.277